Edorium Journal of

Biomedical Science

 
     
Original Article
 
Viral load suppression as a surrogate marker of treatment success in patients on antiretroviral therapy in Namibia
Daniella C Mouton1, Martin Gonzo2, Munyaradzi Mukesi3
1Bachelor of Science, Graduate, Health Sciences department, Namibia University of Science and Technology, Windhoek, Namibia.
2Master of Science, Lecturer, Health Sciences department, Namibia University of Science and Technology, Windhoek, Namibia.
3Master of Science, Lecturer, Health Sciences department, Namibia University of Science and Technology, Windhoek, Namibia.

Article ID: 100002B04DM2017
doi:10.5348/B04-2017-2-OA-1

Address correspondence to:
Munyaradzi Mukesi
Private Bag 13388, Windhoek
Namibia, Windhoek
Namibia, 9000

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How to cite this article
Mouton DC, Gonzo M, Mukesi M. Viral load suppression as a surrogate marker of treatment success in patients on antiretroviral therapy in Namibia. Edorium J Biomed Sci 2017;2:1–8.


Abstract
Aims: The study aimed to establish viral load suppression in patients on different antiretroviral regimens in Namibia.
Methods: This was a retrospective cross-sectional study conducted at the Windhoek Central hospital (WCH) antiretroviral therapy (ART) clinic from 2014–2015. The study population included 302 patients on different ART regimens during the period of 2014–2015.
Results: Out of these patients 225 were females (74.5%) and 77 were males (25.5%). The age range of the respondents was 16–73 years old with a mean age of 34.6 years old. Most of the patients (93%) had good adherence to treatment. The majority of the patients (93.9%) on ART achieved viral load suppression after six months, with 93.3% of the patients maintaining suppression of the viral load after 12 months. Most of the patients on TDF/3TC/EFV (95.2%) suppressed viral load after 12 months. The regimen associated with the highest number of patients (n=5) who failed viral load was TDF/3TC/EFV.
Conclusion: Viral load suppression in Namibian patients was better than results recorded in the United States of America and other countries in Sub-Saharan Africa.

Keywords: Antiretroviral therapy, Namibia, Suppression, Viral load


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Author Contributions:
Daniella C. Mouton – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Martin Gonzo – Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Munyaradzi Mukesi – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Daniella C. Mouton et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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